2- hand foot syndrome

1- clinical manifestation of the sickle cell anaemia

2- caused by painful infarcts of the digits and dactylitis - HAND FOOT SYNDROME

3- out of the context but still just to tell u , IN SICKLE CELL ANAEMIA THE STROKE IS ESPECIALLY COMMON IN CHILDREN , A SMALL SUBSET OF WHOM TEND TO SUFFER REPEATED EPISODES , STROKE IS LESS OFTEN IN ADULTS AND IS OFTEN HEMORRHAGIC.

4- acute venous obstruction of the spleen in sickle cell anemia patients is called SPLENIC SEQUESTRATION CRISIS , rare occurence in early childhood .

5- spleen is frequently lost within the first 18 to 36 months of life causing susceptibility to infection particularly the PNEUMOCOCCI in sickle cell anaemia children.